Phylogeny-based Protein Function Prediction
SIFTER (Statistical Inference of Function Through Evolutionary Relationships) is a statistical approach to predicting protein function that uses a protein family's phylogenetic tree, as the natural structure for representing protein relationships.
Run SIFTER on your local machine:
You can acesses the user-friendly pipeline for large scale protein function prediction using SIFTER algorithm at SIFTER GitHub page.
You can download necessary data for the pipeline from the following links:
- SQL database [34GB]
- Pfam families data [25GB]